Professor Lu has discovered Pin1 and shown that Pin1-catalyzed cis-trans isomerization after phosphorylation catalyzed is a pivotal novel signaling mechanism in diverse cellular processes. Moreover, Dr. Lu has uncovered the unexpected and opposite effects of Pin1 deregulation on the development of cancer and Alzheimer’s disease, which has not only provided the first link between these major diseases that were rarely studied together before, but also offered a promising new paradigm for their diagnosis and treatment. Dr. Lu has served on editorial boards of numerous journals and review committees for the NIH and many other foundations.


Porunelloor A. Mathew, Professor Porunelloor A. Mathew, University Of North Texas Health Science Center, USA, Doctor Porunelloor A. Mathew, Porunelloor A. Mathew biography, scientific conferences, Cancer Science-2013 conference

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