Maria Silvia Mariani Pires de Campos

Maria Silvia Mariani Pires de Campos

Methodist University of Piracicaba, Brazil

Title: The effect of the cryotherapy on the human adipose tissue and pigs isolated adipocytes


Maria Silvia Mariani Pires de Campos graduated in Physical Therapy at Methodist University of Piracicaba (1983), Master in Education (emphasis in Motor Education) at the Methodist University of Piracicaba and Ph.D. in Functional and Molecular Biology (Physiology) at the State University of Campinas (2004). She is a Professor of physical therapy graduate and coordinator of physiotherapy dermatology functional post graduation courses at Methodist University of Piracicaba. She has experience in the area of dermatology and endocrinology physiotherapy, research on effi cacy of cosmetics therapies, electrotherapy and isolated adipocytes. She is member of CREFITO-3 and president of the Scientifi c Committee of the Brazilian Association of Dermato-Functional Physical Therapy (ABRAFIDEF).a


The use of cryotherapy is widely used in cosmetic clinics in Brazil promising the reduction of the localized fat, although there is no study that proves its eff ectiveness or its mechanisms of action. However, we fi nd in the scientifi c literature evidences that the exposure to low temperatures environments, as well, the immersion of the body into cold water were effi cient to induce lipolysis. Th e treatments at the clinics are always performed with hydroalcoholic gels or solution with camphor and mint which promotes an eff ect of cold sensation without scientifi c evidence of their results. So, initially we aimed to evaluate clinically, through ultrasonography, perimetry and cutaneous fold the chronic eff ect of the cryotherapic bandage (CB) in healthy women which do not use oral contraceptives. Aft er 12 sessions, there is a signifi cant reduction in the thickness of abdominal adipose tissue. We also investigate through heart rate variability and ergoespirometry that CB treatment induces a moderate hypothermia, and an increase in the sympathetic tone associated to an increase of the basal metabolism in lean men, but these eff ects did not occur in overweight individuals. In isolated adipocytes from pigs, the association of cryotherapy with the phonophoresis with caff eine was tested, and we observed that the cryotherapy aft er the phonophoresis, is capable to increase the basal lipolytic activity. Th ese results allow us to strongly suggest that the use of cryotherapic bandage is effi cient to reduce localized fat.

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