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Biography

Michael Kamrava earned a Bachelor of Science in physiology with high honors from University of Illinois, USA and graduated from Case Western Reserve Medical School in 1976 with honors in endocrinology. Following a residency in OB/GYN, I finished a fellowship in Reproductive Endocrinology and Infertility at Beth Israel Hospital, Harvard Medical School, USA. I served as clinical instructor in OB/GYN at UCLA. I was a principal investigator on the use of subcutaneous pulsatile GnRH in ovulation induction. I have been on the editorial staff of several scientific journals and have published numerous articles and book chapters and have been the editor of a book entiltled “Ectopic Pregnancy”. I have been an invited speaker at several national and international talks and conferences and have participated in conducting endoscopic workshops. I have been awarded the “Golden Telescope” for introducing the SEED technique for embryo implantation with visually directed endoscopic control of embryo implantation and subsequently have innovated the HEED embryo transfer for the early stage embryo transfers. In private practice of nearly 30 years, I have helped thousands of patients in their struggle with infertility to achieve their dreams of parenthood come true.

Abstract

INTRODUCTION There has been little change in embryo transfer technique in past 30 years, even though it is a major bottleneck to the success of IVF procedure. Here we would like to share our experience with endoscopic embryo transfer and implantation. MATERIALS AND METHODS In the first group of patients HEED was done on day 2/3, and in the second group SEED was done on day 5/6 after oocyte retrieval. The hysteroscope was a 3mm flexible scope made by Storz, El Segundo, CA, USA and the KAM's catheter was made by IVF Scientific, Beverly Hills, CA USA. RESULTS There were a total of 59 patient starts with a total of 32 pregnancies. There were 14(24%) live births, 6 biochemicals, and 10 spontaneous pregnancies. The 2 ectopic pregnancies were confined to the HEED group. DISCUSSION HEED and SEED are objective and reliable techniques that assure correct placement of the embryo(s). Ectopic pregnancies from IVF will be minimized by using lower transfer volumes of 5 µl and visually confirmed positional placement of embryos 2 cm away from the uterine cornu and are eliminated with SEED. Patients with failed IVF, 'Implantation Failure' or at risk for ectopic pregnancy would particularly benefit from SEED. The use of endoscopic embryo transfers would greatly alleviate patient anxiety as they can see the transfer process on the monitor, and would decrease cost to the patient as they decrease the number of attempts at using IVF in achieving a successful targeted singleton pregnancy.