Mohammad Mehdi Sedaghat
Tehran University of Medical Sciences
Dr. Sedaghat is Associate Professor at Tehran University of Medical Sciences (TUMS). He completed his doctoral study in integrated molecular and morphological systematic of Anopheles at the school of Public Health, Tehran University of Medical Sciences and Natural History Museum , London in 2002.He is head of Vector Biology lab and acts as research deputy of department of Medical Entomology and Vector Control at TUMS. His area of interest includes medical and molecular entomology and also vector control using natural products.He has published many research and review articles in the international peer reviewed journals and served as reviewer of the reputed journals in these fields.
Anopheles mosquitoes are the most important vectors among the arthropods. Human Malaria is transmitted through the bites of female Anopheles mosquitoes. It is estimated that malaria is responsible for 627 000 deaths globally. The usage of natural products as larvicides considered as a significant methods for mosquito control. Natural products have beneficial advantages including efficacy, degradability and non-toxic effects on non-target organisms.Based on laboratory and field experiences, descriptive studies or reports, six categories are considered for larvicidal activity of natural products derived from plants including extremely active, highly active, active, moderately active, slightly active and non active. This guidance suggests the likely larvicidal activity of plant essential oils based on the LC50 value. We consider natural products derived from plants extremely active when its LC50 is up to 1, highly active when its LC50 is between 1-5, active when its LC50 is between5-50, moderately active when its LC50 is between 50-100, slightly active when its LC50 is between 100-200 and non active when its LC50 is more than 200. It seems three classes extremely active, highly active and active are required more attention, while there is no priority of research for the rest of categories.