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Biography

Nothabo Dube is a graduate student in the department of Mathematics and Statistics at Texas Tech University studying towards a PhD in Mathematics.

Abstract

Dendritic cells play an important role in linking the innate and adaptive immune mechanisms. The effect of an Mtb vaccine that specifically targets Dendritic cells is studied. A model with T and CTL mechanisms is first studied, then a model with T, CTL and Dendritic cells and finally a model with a dendritic cell-based vaccine. From the model analysis, a cell-based vaccine can help effectively control Mtb infection

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