R. S. Dubey
Banaras Hindu University, India
Dubey was born on Dec. 23, 1955 in Dist. Siwan (Bihar). He obtained M.Sc. degree in Biochemistry from Banaras Hindu University in 1976 standing 1st in order of merit and Ph.D. degree in Biochemistry in 1980. He possesses over 37 years of experience of research and over 31 years experience of teaching. He served as Scientist S-1 in Indian Council of Agricultural Research for 4 years (during 1978-82), Lecturer at Banaras Hindu University for 8 years (during 1983-1991), Reader for 8 years (from 1991 to 1999) and Professor of Biochemistry at Banaras Hindu University for 15 years. At Banaras Hindu University he has served in various capacities in educational administration such as Head of the Department of Biochemistry for 9½ years (for 4 terms) during 1992-1995, 1997, 2002-2004 and 2011-2013; Professor-In-Charge of BHU Library for over 2 years (September 6, 2006 to December 20, 2008), Coordinator of Hindi Publication Board of BHU for over 6 years (2002-2008) and Coordinator of Alumni Cell of BHU for 2 years (from May 8, 2009 to Nov 4, 2011). He has served as Member in different authorities of other universities such as Member of the Academic Council of Central University of Rajasthan, Member of the Academic Council of Central University of Himachal Pradesh and Member of the Court of North Eastern Hill University, Shillong being nominated by Government of India. Twenty six students have received Ph.D. degrees under his supervision. He has published 138 scientific research articles in national and international peer reviewed journals including 22 Chapters in books. His research interests have been focused in the areas of Stress Metabolism in Crop Plants, Bacterial Enterotoxins and Enzyme Technology. His research contributions have been widely cited by more than 3,800 authors (with h-Index 29 and i-10 Index 60) in various Scientific Articles, Reviews, etc., as evidenced from Google Scholar (http://scholar.google.com/citations?user=S76rQVEAAAAJ). He has been recognized as one of the TOP-TEN MOST CITED AUTHORS by ELSEVIER publications for the years 2003-2008 for his work published in the journal Plant Science. He has completed 6 major scientific Research projects funded by national funding agencies like ICAR, MOEn, UGC, DST, etc. He is recipient of Banaras Hindu University Medal in 1976 for securing 1st rank in M.Sc.(Biochemistry) examination, Young Scientist Award by Indian Science Congress Association in 1982. After receiving Swedish Institute Fellowship in 1989 he worked at University of Gothenburg, SWEDEN for one year. He was nominated by Indian National Science Academy (INSA, New Delhi) under INSA-DFG (German Academy of Science) exchange programme for three terms of 3 months each and worked in GERMANY at Institute of Plant Genetics and Crop Plant Research Institute, Gaterslaben in the year 1997 and at Institute of Plant Nutrition, Hannover during 2003 and 2007. He was awarded the prestigious JSPS (Japan Society for Promotion of Science) Fellowship and worked at Kyushu University, Japan during May 1998-March 1999 and at the Research Institute for Bioresources, Okayama University, Japan during May 16-July 14, 2005. At Banaras Hindu University as Organizing Secretary, he organized 2 International and 3 national Seminars during 1995-2010. He is Life Member of many Indian Professional Scientific bodies like Indian Science Congress Association, Society of Biological Chemists (India), Society for Plant Biochemistry and Biotechnology, Indian Chemical Society and Indian Society of Agricultural Biochemists. He has served as Member in Executive Committees of Indian Society for Agricultural Biochemists and Society of Plant Biochemistry and Biotechnology. He is a Fellow of Indian Society of Agricultural Biochemists (FISAB), Biotech Research Society (FBRS) of India and Bioved Research Society of India.
Elevated levels of the metals like Cd, Pb, Ni, As, Al in the soil are major challenges in achieving sustainable food production. Industrial activities, waste disposal practices, smelting, alloy processing, indiscriminate use of pesticides and fertilizers add several metals at high levels into the soil environment. Using rice as a model crop we have examined the effects of increasing concentrations of the metals Cd, Pb, Ni, As, Al in the growth medium of rice plants on growth parameters, key metabolic alterations with special reference to production of reactive oxygen species (ROS) such as superoxide radical, H2O2, induction of oxidative stress marked by lipid peroxidation, protein oxidation, the levels of antioxidants ascorbate and glutathione, activities of the antioxidative enzymes superoxide dismutase, catalase, peroxidase as well as proteomic changes in rice plants in sand cultures and hydroponics. Our studies have revealed that oxidative stress is a major contributor involved in metal toxicity induced damage in rice plants. The extent of oxidative injury caused by the individual metals to protein thiols, lipids, and nucleic acids, the role of various isoforms of antioxidative enzymes in combating the oxidative injury, and the specific proteins which are induced under metal toxicity and which could be correlated with metal tolerance have been examined. A unique role of Fe-dependent superoxide dismutase in conferring Al tolerance has been established. Using proteomics approaches, we have identified metal toxicity induced differential expression of many novel proteins such as under-expressed, over-expressed and newly synthesized metal-specific proteins in tissues of rice plants, differing in metal tolerance. Further, the possible alleviation of metal toxicity using salicylic acid and extracts of various plants has been examined. The biochemical parameters associated with tolerance to these metals could be used to engineer metal tolerant crop plants and these parameters would also serve as effective markers for selection of stress tolerant lines in breeding programmes.