Rania Abdel Hay has completed her from Cairo University, Egypt and now she is a postgraduate student in the cosmetic unit of the Dermatology Department, Faculty of Medicine, Cairo University. She has published more than 28 papers in reputed journals and has been serving as an associate editorial board member of repute.


Background: Rejuvenation of the lower face can be challenging and no single modality can accomplish all its complex events. Patients and Methods: Th is 18 month study included 24 female patients with a primary complaint of lower face aging signs. Th ey were randomly allocated to either group A who received injection lipolysis and hyaluronic acid dermal fi ller, or group B who in addition received non ablative 1540 fractional laser. Th e improvement evaluation score used was the global aesthetic improvement scale (GAIS). Patient's satisfaction level was also recorded. Both were repeated at months 6, 13 and 18. Results: At all evaluations, laser group showed higher degree of improvement. Interestingly, at short term evaluation (6 month), there was no signifi cant diff erence between both groups (P>0.05), however the laser group improvement in comparison to the other group became signifi cant in the long-term evaluations (13 and 18 months) (P<0.05). Conclusion: Th is study further documents the importance of combination therapy in facial rejuvenation, off ering a treatment protocol combining injection lipolysis and hyaluronic acid as an eff ective, safe, short term therapeutic option in lower face rejuvenation. Th e addition of 1540 non-ablative fractional laser to the protocol off ers a higher effi cacy with longer-term eff ects and no adverse events.

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