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Biography

A graduate in Bio Science(B.Sc.) from Agra Univ., graduate in Medicine(B.U.M.S.) with Hons., Gold Medalist from Univ. of Delhi, post graduate (M.D.) (Medicine-Unani) from Hamdard Univ. New Delhi, Long Term Training Fellow(ICMR-NIH USA) on Bioethics and Associated Expert on Bioethics for BBB Univ. of UQUESNE, USA. Having experience of 29 years of Applied Clinical Research, besides 07 years experience of teaching as faculty. Presently working as Scientist-IV in CCRUM, Ministry of Health & F.W.,Govt. of India. Published two books and twenty research papers in different National and International Journals. Presented more than 50 papers in different National and International Conferences.

Abstract

Osteoarthrosis is the commonest life style disorder encountered by the society. In the western countries radiographic evidences of this disease is present in majority of persons by 65 years of age and about 80% persons more than 75 years of age; despite exhaustive work, still no satisfactory answer has been placed forward by the modern medicine, conservative measures are ineffective and produce various ADRs. Whereas, the Unani physicians e.g. Galen, Ibn Sina, Razi, Majoosi, Akbar Arzani, Azam Khan & Kabiruddin has suggested FASD as an adjuvent regimental therapy for various types of Arthritis. Though venesection is in vogue, but its scientific validation has not been carried out so far about its safety, efficacy and mechanism of action. Therefore, to explore new alternatives and for scientific validation of Fasd, this study has been designed and carried out to evaluate the safety and efficacy; and to explore the mechanism of action of Fasd in the cases of Osteoarthrosis. Total 40 cases of O.A. was randomly divided into two groups A & B (20 each). Group ‘A’ (Control group) was administered with the standard drugs while Group ‘B’ (Test group) was given the standard drugs as given in group ‘A’ with intervention of venesection. The duration of treatment was fixed 6 weeks. The intervention of Fasd was performed at base line, 14th & 28th day. The pathological, Biochemical (LFT, KFT) Arthritic profile and Radiological examination was performed at base line and last follow up. The intervention FASD (Venesection ) showed statistically significant results in comparison to control group in subsidence of pain, morning stiffness, muscular weakness, but comparable in swelling/effusion and restriction of movement. The test intervention was found safe and well tolerated as evaluated on hematological parameters (Hb, TLC, DLC, ESR), LFTs & KFTs. The communiqué also brings into limelight the possible mechanism of action of Fasd in O.A. by exploiting the knowledge of microcirculation, Haemodynamics; and physical and chemical dimensions of Biohemorrheology.