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Biography

Ya Yuwen received a PhD from China Academy of Chinese Medical Sciences in 2009. Now she is the Associate Researcher of China Academy of Chinese Medical Sciences, and the member of TCM standardization office of State Administration of Traditional Chinese Medicine of P.R.C. She has published more than 80 academic papers in reputed journals and serving as the reviewer of Chinese Journal of Integrated Traditional and Western Medicine.

Abstract

An increasing number of clinical practice guidelines (CPGs) in traditional Chinese medicine (TCM) for rheumatoid arthritis (RA) have been issued, and all have been developed in China but their quality is unclear. This study aimed to systematically review the quality and consistency of recommendations on the TCM CPGs for RA in China using the AGREE II instrument. Methods: TCM CPGs identified from five electronic databases and hand searches through related handbooks published between January 1990 and December 2012. The CPGs were categorized into Evidence Based (EB) guideline, Consensus Based with no explicit consideration of Evidence Based (CB-EB) guideline and Consensus Based (CB) guideline according to the method reported previously. Four reviewers independently appraised the CPGs based on the Appraisal of Guidelines for Research and Evaluation (AGREE II) instrument, and compared the recommendation on TCM pattern (Zheng) classification and treatment. Results: Five TCM CPGs satisfied the inclusion criteria. The quality score of EB guideline was higher than CB-EB and CB guidelines. Five TCM patterns in the CPGs were recommended in the EB CPG. The herbal preparations including Tripterygium wilfordii recommended in the EB CPG were mostly recommended for RA treatment. The recommendations on non-drug management in the CPGs were fairly consistent, and the recommendations are different based on the different TCM patterns accordingly. Conclusions: EB CPG for RA treatment in TCM show higher quality with measurement of AGREE II instrument, and it suggested that TCM CPG could be better developed with clinical evidence.