Shanghai Institute of Planned Parenthood Research, China
Yuyan Li has completed her Ph.D at the age of 34 years from Fudan University. She is an associate researcher of Shanghai Institute of Planned Parenthood Research, and has published more than 50 papers in journals and serving as tutor of student major in epidemiology and health statistics for master degree of Fudan University.
Many studies have found that fetal factors had effects on long-term health, since the fetal origin of adult disease was introduced by Barker in 1986. This study was to explore the effects of maternal gestational and perinatal factors on blood pressure of children. A follow-up study for the birth cohort in Wuxi was conducted in childhood. Questionnaire survey and physical examination, including height, weight, systolic blood pressure (SBP) and diastolic blood pressure (DBP) in childhood were conducted. χ2 test, multi-linear regression and multi-logistic model were used to analyzed data. Total 2256 children were followed up, aged from 10 to 13 years old. Adjusted sex, age and BMI in childhood, live habits of children, maternal gestational and perinatal factors were analyzed in multi-models, which found that maternal occupation had effects on SBP, children whose mother was worker or other had lower SBP, compared with those whose mother was peasant. Compared with children who were first parity, those who was not had higher SBP, and SBP in childhood increased with the birth length’s adding. Compared with children whose mother had no pregnancy-induced hypertension when delivery, those whose mother had it had higher SBP, DBP and the proportion of elevated BP, with OR value was 3.26 (95%CI: 1.91-5.56). So, mothers’ lower social economic status might increase blood pressure of children, and pregnancy-induced hypertension when delivery was a risk factor of blood pressure of children. Some strategies should be conducted to control the pregnancy-induced hypertension.