Ahmed Hegazi

Ahmed Hegazi

National Research Centre

Title: Antibacterial activity of bee venom


Ahmed Hegazi is currently a Professor of Microbiology and Immunology in the National Research Center, Egypt. Prof. Hegazi received his master’s degree in 1979, and his PhD in 1981. Hegazi's research work has been focused lately on bee products and their therapeutic effects. Hegazi organized and contributed to national and international research projects since 1977 and up till now; he has been the principal investigator on multiple research projects within the National Research Center. He has published 207 scientific papers and articles in national and international journals. He also served on the board of multiple national and international scientific journals. Dr. Hegazi is also the president of the Egyptian Environmental Society for Uses and Production of Bee Products, secretary of the Egyptian Society of Apitherapy, secretary general of the African Federation of Apiculture Associations, and a member of the International Apitherapy Commission (APIMONDIA). Dr. Hegazi awards; First Class Decoration of Excellence, Egypt, 1995, The Senior Scientist Prize of National Research Center, Cairo, Egypt, 1996, The National Scientific Prize In Biological Sciences, Egypt, 1990, The Scientific Prize of The National Research Center, Cairo, Egypt, 1989, The Second Best Research Paper Award, International Congress of Propolis, Bones Airs, Argentina, 2000, Main Speaker Award,10th Academic Conference, PRA and NAS (Nippon Apitherapy Soc.) Japan, 2006, 2 Bronze medals from The International Innovation Fair of the Middle East, Kuwait, 2007 Awarded of Ghazi Wad Allah Salon Prize, 2008 and have 4 patents. Patents


Bee venom is very complex mixture of active peptides, enzymes, and amines. The composition of the venom produced by the glands of Apis mellifera has been well documented. The therapeutic application of bee venom, has been used in traditional medicine to treat diseases. It has biological activity as inhibit mammary carcinoma cell proliferation), cytotoxic to malignant cells both in vitro, arthritis, rheumatism, pain, cancerous tumors, and skin diseases, rheumatoid arthritis and osteoarthritis. Honey bee (Apis mellifera) venom therapy (apitherapy) has been elucidated therapeutic value for bacterial diseases and reported to be as effective as antibacterial drugs. Antimicrobial activity on some Gram-negative bacteria as Escherichia coli and Salmonella spp., Enterobacter cloacae, Escherichia coli and Citrobacter freundii and Staphylococcus aureus, Coagulase-negative Staphylococcus and E. coli. The aim of this review was, therefore, to evaluate the data from antimicrobial activity of bee venom.