Loma Linda University Medical Center, USA
Title: Hypertensive heart disease
Deepika Narasimha is a Cardiology fellow at the Loma Linda University Medical Center and her research interests include clinical trials in cardiovascular disease especially coronary artery disease, atrial fibrillation and cardiomyopathies. She have been actively involved in two single center randomized controlled trials as a resident including writing the IRB proposal, enrolling patients, data analysis and manuscript preparation. She is also currently involved in retrospective studies evaluating systolic dysfunction in post liver transplant patients, and pre-operative work-up of renal transplant patients. She was the Chief resident at Internal Medicine residency program and received the 2014-2015 Thomas Frawley research fellowship awarded to upcoming young investigators. She have published several peer reviewed articles, one book chapter, and presented abstracts at various national and regional conferences including the ACC, ISHLT, HRS and ACP meetings.
Hypertension is a major risk factor for cardiovascular morbidity and mortality. The risk for coronary artery disease is doubled, and the risk for congestive heart failure and stroke is tripled in patients with hypertension. In addition to this, hypertensive heart disease itself encompasses a very wide range of disorders including left ventricular hypertrophy, systolic and diastolic dysfunction which can down the line lead to symptomatic heart failure and precipitate arrhythmias. There are several structural and functional changes in hypertensive heart disease which first lead to concentric left ventricular hypertrophy which if left untreated leads to dilated cardiomyopathy or the ‘burned-out’ left ventricle. Cardiac complications from hypertension cause significant morbidity and mortality and also influence the choice of appropriate therapy and diagnostic tests. My talk will focus on the clinical manifestations and natural history of hypertensive heart disease as well as the various diagnostic and therapeutic modalities available to diagnose and treat the same. In addition to these we will also discuss some of the common cardiovascular co-morbidities associated with hypertension including atrial fibrillation, coronary artery disease and concomitant aortic stenosis with hypertension.