Hina Naushad Qureishi
University of Nebraska medical Center, USA
Dr Hina Naushad Qureishi has completed her medical degree from Rawalpindi Medical College, Pakistan. She completed her pathology residency from University of Nebraska Medical Center in Omaha Nebraska, followed by a one-year surgical pathology fellowship at Washington University School of Medicine/Barnes-Jewish Hospital in St. Louis, MO. She also completed a two-year fellowship in hematopathology from University of Nebraska Medical Center. She worked as an assistant professor at Creighton University Medical Center in Omaha where she directed the flow cytometry and hematology laboratories and was also the director for M2 Hematology/Oncology course. Currently she is as an assistant professor in the division of hematopathology at University of Nebraska Medical Center.
The classification of B-cell and T-cell non-Hodgkin lymphoma has changed considerably over the last several decades. The currently used World Health Organization (WHO) classification system has a broader consensus among the clinical and biomedical community. However, there are still several challenges in regards to the understanding of tumor biology, clinical outcome and diagnostic accuracy in certain subtypes of lymphomas such as peripheral T-cell lymphoma (PTCL), where the diagnosis is frequently challenging even among expert hematopathologists and often time’s assessment requires additional molecular testing. Recently genome-wide high throughput techniques have greatly improved our understanding of B and T-cell lymphomas. This novel genetic information has not only aided in diagnosis, but has also revealed a landscape of critical molecular events that determine the biological and clinical behavior of a lymphoma. In this presentation, I will summarize the genetic characteristics of major subtypes of B-cell and T-cell lymphomas including diffuse large B cell lymphoma (DLBCL), follicular lymphoma (FL), Burkitt lymphoma (BL), and mantle cell lymphoma (MCL) and common subtypes of PTCL including angioimmunoblastic T-cell lymphoma (AITL), anaplastic T-cell lymphoma (ALCL), adult T-cell leukemia/lymphoma (ATLL) and extra-nodal NK/T cell lymphoma (ENKTL), and how can these improve precision in diagnosis and inform prognosis.