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Biography

Yu HongYu has been with the Department of EEE at SUSTC since 2011. He received a Bachelors of Engineering from Tsinghua University, he completed his Masters in Applied Science degree from University of Toronto and a PhD degree from National University of Singapore. He was at IMEC (Leuven Belgium) as a senior researcher in the Si process and device technology division. His current major research interests cover sustainable electronic devices, including low-power IC/memory devices, bio-electronics and green photonics/solar cell devices. He has authored and co-authored about 300 publications in the top tied international journals and conferences, with a total over 2000 citations (SCI) and with an H index of 28. He has been invited to give talks for more than 20 international conferences and also invited to write 4 book chapters. He also published and has been granted with 20 USA/EU patents. He is an IET fellow, and has received many awards.

Abstract

As a potential biochemical sensing platform, leaky surface acoustic wave (LSAW) biosensor consists of a special orientation of a piezoelectric crystal and shows superb sensitivity, speed and reliability. In this work, a novel label-free LSAW biosensor for detecting hepatitis B surface antibody (HBsAb) is fabricated. The sensing area of LSAW is coated with 500nm thick gold membrane on a 100MHz LiTaO3 piezoelectric single crystal. Then the hepatitis B surface antigen (HBsAg) is immobilized on the surface of a gold electrode. The phase shift of LSAW is monitored to detect HBsAb, which increases the mass loading of LSAW by binding to immobilized HBsAg. A reference LSAW device is immobilized with bovine serum albumin (BSA) to block binding of HBsAb. This sensor shows great specificity and sensitivity in detecting HBsAb.

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