Mahesh N Sanzgiri
St. Xaviers College, India
Mahesh N Sanzgiri has done his PhD in Organic Chemistry from Bombay University in 1984 under guidance of Prof. V V Nadkarny of St. Xavier’s College, Mumbai. His research is dedicated to study of few derivatives of anthrone and pheromones. His research work for application of derivatives of anthrone in anticancer and anti-aids activity is a new approach with synthesizing organic compounds using functional groups for trapping active cancer cells and removing aids activity. With wide experience in working with multinational German Chemical and Pharma Co. Merck in India for many years on responsible position, presently he works as a Freelance Scientist and Consultant for doing research and development, also consultant for cGMP, WHO, USFDA, ISO etc. with various well-known Indian and multinational Indian and foreign companies.
Isolation, identification and field study on tiger pheromones is concentrated in this work. Pheromones, although well-known in the insect world, not much work has been done in the case of mammals. In order to do the field studies, especially using this as a biochemical marker by tiger in territory marking and communication especially during mating season, the studies were carried out in forest. For the study, tiger urine was collected from different zoos in month of January, March, July and September to cover most of the seasons of the year. For separation of components of tiger urine for study purpose Merck HPTLC and preparative layer chromatographic techniques were used and so also electrophoratic run on Whatsmann’s paper. To confirm functional groups of components separated, IR Spectrum was used. Identification of structure of tiger pheromone molecular weight of tiger pheromone varies from tiger to tiger which indicates tiger pheromone is unique to each tiger. Due to this tiger marks its territory by spreading urine on trees which is identified by other tigers. Molecular weight varies anywhere between 1000-5000.