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MD Ahsan Habib

MD Ahsan Habib

The University of Tokyo, Japan

Title: Development of new ion source/new desorption method for mass spectrometry

Biography

Md. Ahsan Habib has completed his PhD in Analytical Chemistry at the age of 36 years from Saga University, Japan. Currently Dr. Habib working as a JSPS fellow at the University of Tokyo and Professor, Department of Chemistry, University of Dhaka, Bangladesh. Dr. Habib has also completed 06 years 04 post-doctoral research at Saga, Chiba, University of Yamanashi and Yokohama National University in various fields of Chemistry/Science. He has published more than 30 papers in reputed journals and presented in about 30 in national/international seminars/conferences.

Abstract

Detection and quantification of illicit compounds at trace level is very much important for public health, security and safety. Mass spectrometry (MS) has already been demonstrated its versatility for detection and quantification of a wide range of compounds at trace level because MS can provide molecular level information of the target compounds. In MS, there are many ionization sources. So far, none of the ion source can ionize efficiently of a wide range of compounds. For example, electrospray ionization (ESI) and nano-ESI have been widely using for bio-molecules. Nano-ESI has shown better resolution than ESI but it has clogging problem. To overcome such a problem, several attempts have been taken to develop new ionization source, for example, MALDI, probe-ESI (PESI) etc. Recently we have developed new atmospheric pressure chemical ionization (APCI) using alternating current (ac) instead of dc and found as a soft ionization source for explosives detection (Habib et al., RCMS). Moreover, hollow cathode discharge (HCD) ion source has been fabricated for detection of explosives at trace level (Habib et al., RCMS). A desorption method has also been developed using an ultra-cutter to desorb highly non-volatile illicit compounds and ionized dielectric discharge (DBD) ion source, and found better limit of detection (LOD) (Habib et al., ASMS). A vacuum glow discharge ionization (vacuum-GDI) source has been fabricated for the compounds those give negative ions. A further attempt has also been taken to fabricate a hybrid ionization source for polar/non-polar, volatile/non-volatile compounds.