Mostafa Nawar

Mostafa Nawar

University of Alexandria, Egypt

Title: New score to predict response to cardiac resynchronization therapy


Moustafa Mohamed Nawar completed his MBBch in 1975, MSc cardiology 1980, and MD cardiology 1986.Currently he is the Prof. of Cardiology and Head of EP lab, Faculty of Medicine, Alexandria University.


Cardiac resynchronization therapy (CRT) has been used to treat advanced cases of heart failure. How to predict who will respond to CRT remains an important and largely unanswered question. To assess and identify the best predictors of CRT response.170 Patients with heart failure and LVEF<35% were included, the predictors of response assessed including preimplantation clinical, electrocardiographic and echocardiographic variables. CRT response was assessed after 6m.Independent pre implantation predictors of response were the QRS duration>150msec, non-ischemic cardiomyopathy, TAPSE>15 mm, sinus rhythm, absence of COPD and absence of history of renal disease. A new CRTscore to predict responders to CRTwas successfully developed. The score consists of maximum 9 point. The CRT response rate has been markedly different according to the CRTscore with very high response rate if CRTscore>6.The new CRTscore can be useful in patient selection in order to improve the CRT response rate. Validation of the score in different population is highly recommended.