Ibn Tofail Hospital, CHU Marrakech Morocco
Purpose: The increased resistance of uropathogenic bacteria to antibiotics, both in community and hospital settings, justifies the need for periodic regional monitoring of these resistances.
Material & Method: During one-year, we had proceeded to retrospective study from January 1st, 2016 to January 1st, 2017. All urinary specimens of hospitalized patients at Ibn Tofail Hospital and external patients were included in the study. The bacterial identification was made by biochemical gallery ‘Api’ and the susceptibility to antibiotics was tested by antibiogram on agar media according to the recommendations of EUCAST 2016.
Result: During the study period, 523 ECBU were carried out, 69 bacterial strains were isolated, Enterobacteria represented 45 (65%), Escherichia coli dominated the epidemiological profile (45%), followed by Acinetobacter baumannii 11 (16%), then Enterococcus and Staphylococcus aureus with 7%, Pseudomonas aeruginosa 3% and finally Streptococcus spp. (1%). These strains came from hospitalized patients (48%) and external consultants (52%). The susceptibility to antibiotics showed a high frequency of resistance to the main families of antibiotics. About 15% of Enterobacteria were producing extended spectrum β-lactamase (ESBL) and 11% were Carbapenem resistant. Nearly, 55% of AB isolates were resistant to Imipenem. These resistances were accompanied by high rates of co-resistance to other families of antibiotics.
Conclusion: Dissemination of resistant bacteria, particularly ESBL in community and hospital settings, should lead practitioners to a rational prescription of antibiotics, preferably guided by the results of an antibiogram