Stephen Holroyd

Stephen Holroyd

Fonterra Research and Development Centre
New Zealand

Title: Non-targeted methods for detection of food adulteration


Stephen Holroyd is a Research Programme Manager within Fonterra’s External Science & Technology team. His current responsibilities include leadership of research on analytical science and food processing. He has been the Chair of the International Dairy Federation (IDF) Standing Committee on Analytical Methods for Composition (SCAMC). He has 20 years of experience in the implementation of infrared analytical spectroscopy in oil and gas, pharmaceutical and food applications. He has a PhD in Chemistry from the University of Auckland (New Zealand) and Post-doctoral experience at Cambridge University (UK) and has published over 40 papers in peer-reviewed journals.


Food fraud costs the global industry several billion dollars every year, negatively affecting public confidence in food producers and regulators, and can result in unfortunate public health consequences. The use of non-targeted analytical methods to detect and deter adulteration in food ingredients has gained recent interest because of their potential ability to detect new unexpected adulterants that may enter supply chains. A multinational collaborative team led by a US Pharmacopeia expert panel is researching and developing a tool-box of non-targeted analytical methods and supporting reference materials for detecting adulteration in milk ingredients. This presentation will give an update on the outcomes to date of this collaborative effort, including studies conducted to evaluate and develop NIR, Raman, NMR, MALDI‒TOF‒MS, UPLC and wet-chemistry technologies. An update on the advancement of a US Pharmacopeial Convention Guidance on how to develop and validate non-targeted methods will also be provided, with a focus on clear use of terminology and a defined chain of logic for method validation. Lastly, the presentation will highlight the challenges ahead to advance the development and widespread utility of non-targeted methods.