Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest and can lead to a variety of emotional and physical problems. Symptoms of depression are Feelings of sadness, emptiness, angry outbursts, Sleep disturbances, Changes in appetite, Anxiety, Trouble thinking, making decisions etc.
It is estimated that major depression was significantly higher in women (42%) than men (29%) and the genetic risk factors for major depression were moderately correlated in men and women.
To diagnosis Depression various tests like Physical test, Lab tests, Psychological test, Diagnostic and Statistical Manual of Mental Disorders (DSM-5) can be conducted. Medications and psychological counseling (psychotherapy) are very effective for most people with depression. Selective serotonin reuptake inhibitors (SSRIs), Serotonin-norepinephrine reuptake inhibitors (SNRIs), Norepinephrine-dopamine reuptake inhibitors (NDRIs), Atypical antidepressants etc. antidepressant drugs can be used.
Many scientists in Sweden work on Depression, anxiety and their comorbidity in the Swedish general population and doing research that gene therapy may be powerful new treatment for major depression.