Essential thrombocythemia is a chronic disease common in people over age 50 and slightly more common in women. Young people can develop it as well. It is characterised by the overproduction of platelets by megakaryocytes in the bone marrow. Essential thrombocythemia is an uncommon disorder where the body produces too many blood platelets. This condition may cause to feel fatigued, lightheaded and to experience headaches and vision changes. It also increases the risk of blood clots.
The greatest health risk in patients with ET is an increased risk of developing blood clots. Blood clots can be in the deep vessels of the legs or lungs; ET patients are also more likely to experience strokes and heart attacks. ET patients can develop clots elsewhere, including within the abdomen, an otherwise rare site for clots to form. The risk of clotting increases with age, and disease-associated risks may be quite different for children than for adults, with children generally being at low risk for clots and other problems related to ET.
We provide an update on the epidemiology and disease characteristics of tick-borne encephalitis (TBE) in Switzerland. Data were collected through the mandatory notification system of the Federal Office of Public Health. Between 2005 and 2011, a total of 1,055 TBE cases were reported, with a peak of 244 cases in 2006. The average yearly incidence was 2.0/100,000 inhabitants nationwide, with the highest regional value (7.8/100,000) in eastern Switzerland. Incidence by age peaked in 60–69 year-old patients, males predominated in all age groups. Most patients suffered from meningoencephalitis (n=567) or meningitis (n=246), seven of 1,055 patients (0.7%) died.