Nephrotic syndrome is not a disease; it is a constellation of several symptoms that can be caused by several renal diseases. The challenge is to determine any underlying disease causing the nephrotic syndrome in any given patient. Generally, patients with either nephrotic or nephritic syndrome require sub-specialty treatment, and prompt consultation with a nephrologist is advised. Prevalence of behavior disturbance in children with nephrotic syndrome was 68%, significantly higher than that in the control group (21.6%). The behavior abnormalities found in the nephrotic syndrome group were hyperkinesis, obsessive compulsive neurosis, conduct disorder, and emotional disorder, in that order.
The most common cause in younger adults is focal segmental glomerulosclerosis (FSGS), followed by minimal-change nephropathy. Membranous nephropathy is the most common cause in older peopleNephrotic syndrome is rare about 1 in 50,000 children get nephrotic syndrome each year. It affects more boys than girls. It can happen in people of all ages, though often starts when a child is between 2 and 5 years old. Many cases are linked to the immune system, which normally protects the body against disease and infection.