Nonalcoholic fatty liver disease is a term used to describe the accumulation of fat in the liver of people who drink little or no alcohol. Nonalcoholic fatty liver disease is common and, for most people, causes no signs and symptoms and no complications.Prevalence of NAFLD was 19.8% (16.0% in men, 22.8% in women). Prevalence of NAFLD progressively increased with declining adiponectin levels (p for trend < 0.001). Individuals with celiac disease are at increased risk of non-alcoholic fatty liver disease compared to the general population.
The exact cause of NAFLD is still unknown. However, both obesity and insulin resistance probably play a strong role in the disease process. The exact reasons and mechanisms by which the disease progresses from one stage to the next are not known.NAFLD typically shows up as an unexpected abnormality in liver function tests, usually the alanine aminotransferase (ALT) test, in people who otherwise feel well. The elevation of this test generally is minor and in younger patients, does not indicate a serious liver condition. However, if the cause of NAFLD, such as obesity or diabetes, is not treated, the condition may progress.