Pediatric Thrombocytopenia is a condition in which you have a low blood platelet count. Platelets (thrombocytes) are colorless blood cells that help blood clot. Platelets stop bleeding by clumping and forming plugs in blood vessel injuries. Thrombocytopenia often occurs as a result of a separate disorder, such as leukemia or an immune system problem. Or it can be a side effect of taking certain medications. It affects both children and adults. Thrombocytopenia may be mild and cause few signs or symptoms. In rare cases, the number of platelets may be so low that dangerous internal bleeding occurs. Treatment options are available.
In Sweden the total approximately estimated population is 8,986,400 out of this population 25,587 are extarpolated or suffering from this disease or diagnosed
Specific treatments for thrombocytopenia will be determined by your child’s physicians based on the cause and severity of the disease, as well as your child’s tolerance for medications, procedures and therapies. Mild cases may not require treatment and may resolve on their own. Blood transfusions with platelets or red blood cells are sometimes needed.
We do clinical treatment studies, most recently centering around rituximab and the thrombopoietic agents as well as studies also exploring the mechanism of Pediatric thrombocytopenia and various markers connected with it. For example, we have looked at the role of different infectious agents (CMV, H Pylori, HIV) in causing ITP, and we have looked at the effects of thrombopoietic agents on the bone marrow and are attempting to relate responses to platelet antibody types. We collaborate with Paul Basciano on studies of a polymorphism in the H1 domain of beta tubulin for which preliminary data suggests a major role in response to several treatments.