Pulmonary fibrosis is a condition that causes lung scarring and stiffness. It develops when the alveoli, tiny air sacs that transfer oxygen to the blood, become damaged and inflamed. Body tries to heal the damage with scars, but these scars collapse the alveoli and make the lungs less elastic. Changes in the lungs can also increase the blood pressure in the pulmonary artery.
In Sweden the statistical analysis on pulmonary fibrosis gave the result as a total of 324 clinical scenarios were rated: 25% as appropriate; 39%, uncertain; and 36%, inappropriate. The panel disagreed about 12% of the therapy indications in the final ratings, falling from 26% in the first-round ratings. Many people diagnosed with pulmonary fibrosis are initially treated with a corticosteroid. Adding acetylcysteine, a derivative of a natural amino acid, to prednisone may slow the disease in some people.