Pathophysiology: Hepatitis refers to an inflammatory disease which is mainly affects liver. Viral hepatitis is classified as A, B, C, D, E and G. Hepatitis viruses cause liver damage. Inflammation happens throughout liver and hepatocytes are destroyed by cytotoxic cytokines and natural killer cells. Cellular necrosis occur but liver usually able to repair itself and regain complete function if no other complications occur. There are three phases: Prodromal phase, Icteric phase and Recovery phase.
Disease Statistics: In recent year HepC has been a notifiable disease in Sweden. In a study it was found that the Swedish HCV epidemic is highly related to the increase of intravenous drug use.
Treatment: Intravenous rehydration is given as supportive care but no specific emergency treatment is recommended as such. Patients are admitted in conditions of severe complications. Evaluation for hepatic encephalopathy is done. Certain patients may benefit from pharmacologic therapy. Patients are advised to avoid prolonged or vigorous physical exertion until their symptoms improve and maintain adequate hydration
Research: Some of the primary institutes working in for viral hepatitis are Swedish Institute for Infectious Disease Control, Solna; Örebro University, Örebro and others. European Centre for Disease Prevention and Control (ECDC), Stockholm provides funding for the research studies in Hepatitis.