Hodgkin disease: This is a cancer that develops in the lymph system (lymphoma), part of the body's immune system. Because there is lymph tissue in many areas of the body, Hodgkin disease can start in almost any part of the body
The disease most often develops on the background of good health and the absence of any complaints. Mild and non-permanent signs of the disease may hinder early diagnosis. The main symptoms of Hodgkin's lymphoma which causes the patient to seek medical attention are: Painless swelling of subcutaneous lymph nodes in the neck, armpits or groin, Cough and shortness of breath. e and weakness, Periodic hyperthermia, often accompanied by chills, Night sweats, , Decreased appetite and significant weight loss, Increased sensitivity to the effects of alcohol, which is manifested by pain in the lymph nodes after its use Repeated bacterial, viral and fungal infections characterized by its severity.
Treatment of Hodgkin lymphoma is tailored to disease type, disease stage, and an assessment of the risk of resistant disease. Hodgkin lymphoma is considered to be a curable malignancy, a Danish-Swedish case-control study including 3055 NHL patients and 3187 population controls. Thus, treatment focuses on tailoring therapy to each patient according to age, risk of short-term and long-term toxicity, and risk of relapse. Short-term toxicity varies based on the regimen and modalities used (chemotherapy, radiation, combination of both, and stem cell transplantation) and include: Hematologic toxicity: Anemia (need for transfusion), thrombocytopenia, increased risk of infection (febrile neutropenia)Pulmonary toxicity, particularly if bleomycin or thoracic radiation are usedCardiac toxicity from antracycline therapy Treatment-related toxicity that can lead to death.