Meniere's disease can simply be described as an unstable inner ear. Since the inner ear is the site of the sense organs of hearing and balance, patients with Meniere's disease have symptoms of fluctuating hearing loss, attacks of vertigo, and ringing in the affected ear.
Hissing, buzzing or roaring tinnitus during vertigo attack or aural fullness in the ear with hearing loss. Unless the ear involved is profoundly deaf, there must be fluctuation. The aural fullness that accompanies vertigo spells should not be relieved by "popping" of the ears.The cause of Meniere’s disease isn’t known, but scientists believe it’s caused by changes in the fluid in tubes of the inner ear.
The condition affects men and women, and usually begins between the ages of 20 and 50. Usually only one ear is affected, although 10% to 15% of people with Ménière's disease develop it in both ears.This disorder causes vertigo (a sensation of spinning), hearing problems, and a ringing sound in the ear. Meniere’s disease usually affects only one ear.
If vertigo attacks associated with Meniere's disease are severe and debilitating and other treatments don't help, surgery might be an option. Procedures include: Endolymphatic sac procedure. In endolymphatic sac decompression, a small portion of bone is removed from over the endolymphatic sac. In some cases, this procedure is coupled with the placement of a shunt, a tube that drains excess fluid from your inner ear.
Major research on disease:
"Familial clustering and genetic heterogeneity in Meniere's disease".The endolymphatic sac plays a role in regulating inner ear fluid levels. These surgical procedures may alleviate vertigo by decreasing fluid production or increasing fluid absorption.Many people diagnosed with Meniere’s disease will go into remission within a few years after their diagnosis.