Pulmonary valve stenosis is a condition characterized by obstruction to blood flow from the right ventricle to the pulmonary artery. This obstruction is caused by narrowing (stenosis) at one or more points from the right ventricle to the pulmonary artery. The most common form of pulmonary stenosis is obstruction at the valve itself, referred to as pulmonary valvar stenosis.
Pulmonary valve stenosis signs and symptoms vary, depending on the extent of the obstruction. People with mild pulmonary stenosis usually don't have symptoms. Pulmonary valve stenosis signs and symptoms may include Heart murmur - an abnormal whooshing sound heard using a stethoscope, caused by turbulent blood flow, Shortness of breath, especially during exertion, Chest pain, Loss of consciousness (fainting), Fatigue.
Statistical analysis of pulmonary valve stenosis around the Switzerland has given the result as pre-operative PFTs showed markedly elevated airways resistance (RRS) (median 0.45 cmH2O/mL/sec, range 0.17-0.66) and marked variability of the static compliance of the respiratory system (CRS) (median 0.6 mL/cmH2O/kg, range 0.25-2.6). Flow-volume loops measured by forced deflation showed flow limitation within the medium to small airways. Post-operative FVC was reduced in four of the five patients (median 46 mL/kg, IQR 42.9 - 48.8 mL/kg). Patients studied with various levels of positive end expiratory pressure (PEEP) showed improvement in tidal volume and reduced obstruction with PEEP greater than 10 cmH2O. For three patients with pre-operative data available, surgical correction resulted in near-normal post-operative CRS and improved, but still elevated RRS (median 0.14 cmH2O/mL/sec, interquartile range [IQR] 0.11-0.31).