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Transcriptomics is a total set of transcripts in a given organism and referred to as an expression profiling that examines the expression level of mRNAs in a given cell population. Transcriptomics includes high-throughput techniques based on DNA microarray. Transcriptomics:Open Access Journal is at higher echelons that enhance the intelligence and information dissemination on topics closely related to Transcriptomics. They provide a unique forum dedicated to scientists to express their research articles, review articles, case reports and short communications on an array of Transcriptomics. Transcriptomics:Open Access Peer Reviewed Journal is proficiently supported by universally prominent Editorial Board members.
The Journal is using Editorial Manager System for quality in review process.Editorial Manager System is an online manuscript submission, review and tracking systems. Review processing is performed by the editorial board members of Transcriptomics: Open Access or outside experts; at least two independent reviewers approval followed by editor approval is required for acceptance of any citable manuscript. Authors may submit manuscripts and track their progress through the system, hopefully to publication. Reviewers can download manuscripts and submit their opinions to the editor. Editors can manage the whole submission/review/revise/publish process.
The glycome is the entire complement of sugars, whether free or present in more complex molecules, of an organism. An alternative definition is the entirety of carbohydrates in a cell. The glycome may in fact be one of the most complex entities in nature. Glycomics, analogous to genomics and proteomics, is the systematic study of all glycan structures of a given cell type or organism and is a subset of glycobiology. Glycans play a central role as potential mediators between complex cell societies, because all living organisms consist of cells covered with diverse carbohydrate chains reflecting various cell types and states. However, we have no idea how diverse these carbohydrate chains actually are. The main purpose of this article is to persuade life scientists to realize the fundamental importance of taking some action by becoming involved in "glycomics". "Glycome" is a term meaning the whole set of glycans produced by individual organisms, as the third bioinformative macromolecules to be elucidated next to the genome and proteome.
Related Journals of Glycome
Transcriptomics, Journal of Genetic Syndromes & Gene Therapy, Gene Technology, Journal of Medical Microbiology & Diagnosis, Glycobiology, Glycoconjugate Journal, Genomic Insights, Genome Mapping and Genomics in Animals, Genome Integrity
The transcriptome is the set of all RNA molecules, including mRNA, rRNA, tRNA, and other non-coding RNA transcribed in one cell or a population of cells. It differs from the exome in that it includes only those RNA molecules found in a specified cell population, and usually includes the amount or concentration of each RNA molecule in addition to the molecular identities. The human genome is made up of DNA (deoxyribonucleic acid), a long, winding molecule that contains the instructions needed to build and maintain cells. These instructions are spelled out in the form of "base pairs" of four different chemicals, organized into 20,000 to 25,000 genes. For the instructions to be carried out, DNA must be "read" and transcribed - in other words, copied - into RNA (ribonucleic acid). These gene readouts are called transcripts, and a transcriptome is a collection of all the gene readouts present in a cell.
Related Journals of Transcriptome
Transcriptomics, Cell & Developmental Biology, Journal of Molecular Biomarkers & Diagnosis, Journal of Tissue Science & Engineering, Clinical and Translational Oncology, Current Signal Transduction Therapy, Drug Delivery and Translational Research
A microarray is a multiplex lab-on-a-chip. It is a 2D array on a solid substrate (usually a glass slide or silicon thin-film cell) that assays large amounts of biological material using high-throughput screening miniaturized, multiplexed and parallel processing and detection methods.The DNA microarray is a tool used to determine whether the DNA from a particular individual contains a mutation in genes like BRCA1 and BRCA2. The chip consists of a small glass plate encased in plastic. Some companies manufacture microarrays using methods similar to those used to make computer microchips. On the surface, each chip contains thousands of short, synthetic, single-stranded DNA sequences, which together add up to the normal gene in question, and to variants (mutations) of that gene that have been found in the human population.
Related Journals of Microarray
Transcriptomics, Journal of Molecular Biomarkers & Diagnosis, Journal of Down Syndrome & Chromosome Abnormalities, Human Genetics & Embryology , Single Cell Biology, Annals of Human Genetics, Applied and Translational Genomics, Australian Journal of Medical Science, Behaviour Genetics
Protein engineering is the process of developing useful or valuable proteins. It is a young discipline, with much research taking place into the understanding of protein folding and recognition for protein design principles.Several other technological developments contributed in parallel to establishing Protein Engineering as a productive field of research. These include: (i) the development of efficient bacterial systems for expression of a variety of foreign proteins, (ii) the discovery of efficient protein selection techniques such as the phage-display technology and the two hybrids system and, (iii) the progress accomplished in structural biology through extensive and refined application of X-ray diffraction techniques as well as the development of 2D NMR.
Related Journals of Protein Engineering
Transcriptomics, Journal of Proteomics & Bioinformatics, Enzyme Engineering, Journal of Data Mining in Genomics & Proteomics, Journal of Bioprocessing & Biotechniques, Protein Engineering Design and Selection, Protein Journal, Protein Expression and Purification, Protein Science, Current Protein and Peptide Science
The proteome is the entire set of proteins expressed by a genome, cell, tissue or organism at a certain time. More specifically, it is the set of expressed proteins in a given type of cell or organism, at a given time, under defined conditions. The term is a blend of proteins and genome. Proteomics is the study of the proteome.
Related Journals of Proteome
Transcriptomics, Journal of Tissue Science & Engineering, Advances in Genetic Engineering & Biotechnology, Journal of Proteomics & Bioinformatics, Journal of Data Mining in Genomics & Proteomics, Journal of Proteome Research, Journal of Proteome Research and Bioinformatics, Journal of Proteomics, Proteome Science, Proteomics.
Metabolomics is the scientific study of chemical processes involving metabolites. Specifically, metabolomics is the "systematic study of the unique chemical fingerprints that specific cellular processes leave behind", the study of their small-molecule metabolite profiles. The metabolome represents the collection of all metabolites in a biological cell, tissue, organ or organism, which are the end products of cellular processes.
Related Journals of Metabolome
Transcriptomics, Advances in Molecular Diagnostics, Journal of Clinical & Medical Genomics, Metabolomics, Metabolic Engineering, Metabolism, Clinical and Experimental, Metabolic Brain Disease, Journal of Drug Metabolism & Toxicology
The term non-coding RNA is commonly employed for RNA that does not encode a protein, but this does not mean that such RNAs do not contain information nor have function. Although it has been generally assumed that most genetic information is transacted by proteins, recent evidence suggests that the majority of the genomes of mammals and other complex organisms is in fact transcribed into ncRNAs, many of which are alternatively spliced and/or processed into smaller products
Related Journals of Non Coding mRNA:
Transcriptomics, Cloning & Transgenesis, Gene Technology, Advancements in Genetic Engineering, Journal of Clinical & Medical Genomics, Current Protocols in Nucleic Acid Chemistry, Journal of Nucleic Acids, Journal of Nucleic Acids Investigation, Molecular Therapy - Nucleic Acids
Sequencing is the process of determining the order of nucleotide bases (A,C,T, and G) within a stretch of DNA. Sequencing the entire complement of DNA, or genome, of many animal, plant, and microbial species is indispensable for basic biological and medical research.
Related Journals of Sequencing
Transcriptomics, Journal of Genetic Syndromes & Gene Therapy, Journal of Molecular and Genetic Medicine, Journal of Tissue Science & Engineering , Fungal Genomics & Biology, Cytogenetic and Genome Research, Genome Biology, Genome Biology and Evolution, Genome Dynamics, Journal of Next Generation Sequencing & Applications
Forensic DNA profiling (also called DNA testing or DNA typing) is a technique employed by forensic scientists to identify individuals by characteristics of their DNA. DNA profiles are a small set of DNA variations that are very likely to be different in all unrelated individuals. Genes make up the blueprint for our bodies, governing factors such as growth, development and functioning. Almost every cell in the human body contains a copy of the blueprint, stored inside a special sac called the nucleus. The estimated 23,000 genes are beaded along tightly bundled strands of a chemical substance called deoxyribonucleic acid (DNA).
Related Journals of Profiling
Transcriptomics, Journal of Genetic Syndromes & Gene Therapy,Journal of Molecular and Genetic Medicine, Journal of Clinical & Medical Genomics, Cellular and Molecular Biology, Genetical Research, Gene Therapy and Regulation, Geneesmiddelenbulletin,Genetic Engineering and Biotechnology News, Genes Brain and Behaviour.
A typical gene expression data set records the expression level of every gene in a biological sample. Common analysis of such data involves (demonstrating that many genes are differentially expressed in the sample, i.e., the biological condition has a “transcriptomic signature” that is then explored further,characterizing the differentially expressed genes (DEGs) that form the transcriptomic signature, and inferring components of the transcription regulatory networks (TRNs) that are responsible for the observed transcriptomic signature.
Related Journals of Comparative Transcriptomics
Transcriptomics, Gene Technology, Journal of Genetic Syndromes & Gene Therapy, Journal of Tissue Science & Engineering, Transcription, Transgenic Research, Transfusion, Translational Behavioral Medicine
Transcriptome analysis may involve characterization of all transcriptional activity (coding and non-coding), or a select subset of RNA transcripts within a given sample. Illumina offers a variety of sequencing and array solutions to enable rapid profiling of the entire transcriptome, all expressed genes, or targeted transcripts of interest
Related Journals of Transcriptome analysis
Transcriptomics, Journal of Molecular and Genetic Medicine, Cloning & Transgenesis, Journal of Clinical & Medical Genomics, Translational neuroscience, Translational Oncogenomics, Translational Oncology, Translational Proteomics
The Mouse Transcriptome Project utilizes Massively Parallel Signature Sequencing (MPSS) to profile RNA populations from a large number of rigorously collected mouse tissues. MPSS utilizes microbeads to capture and quantify tags for mRNAs isolated from tissues or cells; identity of the mRNAs is determined by sequencing of cDNA fragments attached to the beads. The C57BL/6J mouse was chosen as the source for tissues since the mouse offers consistency of genetic background, premorbid state, and tissue acquisition, as well as detailed genome information. These are essential elements for the creation of a meaningful gene expression dataset.
Related Journals of Mouse Transcriptome
Transcriptomics, Human Genetics & Embryology, Cloning & Transgenesis, Journal of Molecular and Genetic Medicine,
Incorporative Mouse Genome, Advances in Genetics, American Journal of Medical Genetics, Animal Genetics
Microbial transcriptome and metatranscriptome information is important for predicting resistance to specific antibiotics, understanding host-pathogen immune interactions, quantifying gene expression changes, and tracking disease progression. Next-generation RNA-Seq (RNA sequencing) of bacteria, viruses, and other microbes has become a standard method for analyzing transcriptome and metatranscriptome information
Related Journals of Bacterial Transcriptome
Transcriptomics, Fungal Genomics & Biology, Journal of Antivirals & Antiretrovirals, Virology & Mycology,Journal of Medical Microbiology & Diagnosis, Advances in Microbial Physiology, Anti Microbial Agents and Chemotheraphy, Aquatic Microbial Ecology, Enzyme and Microbial Technology
MicroRNA sequencing (miRNA-seq), a type of RNA-Seq, is the use of next-generation sequencing or massively parallel high-throughput DNA sequencing to sequence microRNAs, also called miRNAs. miRNA-seq differs from other forms of RNA-seq in that input material is often enriched for small RNAs. miRNA-seq allows researchers to examine tissue-specific expression patterns, disease associations, and isoforms of miRNAs, and to discover previously uncharacterized miRNAs. Evidence that dysregulated miRNAs play a role in diseases such as cancer
Related Journals of Small RNA Sequencing
Transcriptomics, Single Cell Biology, Journal of Down Syndrome & Chromosome Abnormalities, Journal of Tissue Science & Engineering, Recent Patents on DNA and Gene Sequences, Application of Clinical Genetics,BAG- Journal of Basic and Applied Genetics, Balkan Journal of Medical Genetics
Transcriptional attenuation is a regulatory mechanism that causes premature termination of transcription under certain conditions, thereby preventing the expression of the mRNA required for expression of the corresponding gene products. Premature termination of transcription, or attenuation, is an efficient RNA-based regulatory strategy that is commonly used in bacterial organisms. Attenuators are generally located in the 5′ untranslated regions of genes or operons and combine a Rho-independent terminator, controlling transcription, with an RNA element that senses specific environmental signals.
Related Journals of Transcriptional Attenuation
Transcriptomics, Gene Technology , Journal of Medical Microbiology & Diagnosis, Journal of Clinical & Medical Genomics, American Journal of Biochemistry and Molecular Biology, American Journal for Respiratory Cell and Molecular Biology, Asia Pacific Journal of Molecular Biology and Biotechnology, Biochemistry and Molecular Biology Education
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Genes encode proteins and proteins dictate cell function. Therefore, the thousands of genes expressed in a particular cell determine what that cell can do. Moreover, each step in the flow of information from DNA to RNA to protein provides the cell with a potential control point for self-regulating its functions by adjusting the amount and type of proteins it manufactures.
Related Journals of Gene Expression Profiling
Transcriptomics, Journal of Tissue Science & Engineering, Advancements in Genetic Engineering, Journal of Molecular Biomarkers & Diagnosis,Genes Chromosomes and Cancer, Gene Expression, Genes and Immunity, Genetic Engineering and Biotechnology Journal, Genes
In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity. A single gene can be regulated in a range of ways, from altering the number of copies of RNA that are transcribed, to the temporal control of when the gene is transcribed. It is estimated that the human genome encodes approximately 25,000 genes, about the same number as that for corn and nearly twice as many as that for the common fruit fly. Even more interesting is the fact that those 25,000 genes are encoded in about 1.5% of the genome. So, what exactly does the other 98.5% of our DNA do? While many mysteries remain about what all of that extra sequence is for, we know that it does contain complex instructions that direct the intricate turning on and off of gene transcription.
Related Journals of Transcriptional Regulation
Transcriptomics, Gene Technology, Journal of Genetic Syndromes & Gene Therapy, Human Genetics & Embryology, Gene, Gene Expression, Gene Expression Patterns, Genes and Genetic Systems, Genes and Genomics
*2016 Journal Impact Factor was established by dividing the number of articles published in 2014 and 2015 with the number of times they are cited in 2016 based on Google Scholar Citation Index database. If 'X' is the total number of articles published in 2014 and 2015, and 'Y' is the number of times these articles were cited in indexed journals during 2016 then, journal impact factor = Y/X