Acanthosis nigricans is a common skin pigmentation disorder. The sign of acanthosis nigricans are usually found as dark patches of skin with a thick, velvety texture. It is usually found in body folds, such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead, and other areas.
The skin changes of acanthosis nigricans (ak-an-THOE-sis NIE-grih-kuns) typically occur in people who are obese or have diabetes. Children who develop the condition are at higher risk of developing type 2 diabetes. Rarely, acanthosis nigricans can be a warning sign of a cancerous tumor in an internal organ, such as the stomach or liver.
Disease statistics: In United Kingdom the prevalence rate for Acanthosis nigricans was calculated by considering a total of 2,205 participants were examined. Overall prevalence rates for Acanthosis nigricans were 34.2 and 47.2%, respectively. In general, the rates for both increased with age and degree of Indian heritage and were higher in female subjects, overweight/obese individuals, those with type 2 diabetes, and those with a parental history of type 2 diabetes.