Normally, blood cells are made in the bone marrow in an orderly and controlled way. In people with AML, this process gets out of control and many abnormal leukaemia cells are made. In 2011, there were 2,921 new cases of AML in the UK: 1,608 (55%) in males and 1,313 (45%) in females, giving a male:female ratio of around 12:10.The crude incidence rate Open a glossary item shows that there are 5 new AML cases for every 100,000 males in the UK, and 4 for every 100,000 females.
looking pale and feeling tired and breathless, which is due to anaemia caused by a lack of red blood cells, having more infections than usual, because of a lack of healthy white blood cells, unusual bleeding caused by too few platelets - this may include bruising (bruises may appear without any apparent injury), heavy periods in women, bleeding gums, nosebleeds and blood spots or rashes on the skin (petechiae)
Most people with AML are referred to a specialist haematology unit in the hospital. The haematologist will ask about your general health and any previous medical problems you’ve had. They’ll examine you to check if your lymph nodes, spleen or liver are enlarged. You’ll also have more blood samples taken to check the number of different cells in your blood and to look for leukaemia cells.