It is a condition, which is characterized by delays the social function, speech as well as motor skills. The cause of childhood disintegrative disorder is unknown. Childhood disintegrative disorder is also known as Heller's syndrome and disintegrative psychosis. Delay or lack of spoken language, Impairment in nonverbal behaviours, Inability to start or maintain a conversation, Lack of play, Loss of bowel and bladder control, Loss of language or communication skills, Loss of motor skills, Loss of social skills, Problems forming relationships with other children and family members. The prevalence of Childhood disintegrative disorder is 1 in 100,000 boys and ratio of boys to girls is estimated to be 8 boys to 1 girl.