Coronary artery disease (CAD) is the most Common type of heart disease, also referred to as coronary heart disorder. Coronary arteries are the essential blood vessels that supply your heart with blood, oxygen and nutrients. CAD occurs when these that provide blood to coronary heart muscle turn out to be hardened and narrowed. Atherosclerosis (regularly known as “hardening” or “clogging” of the arteries) is the buildup of cholesterol and fatty deposits (referred to as plaques) on the internal walls of the arteries. These plaques can avert blood go with the flow to the center muscle by clogging the artery or via causing abnormal artery tone and function.
Cardiovascular (heart and circulatory) disease causes more than a quarter of all deaths in the UK, or around 155,000 deaths each year - an average of 425 people each day or one every three minutes. Around 41,000 people under the age of 75 in the UK die from CVD each year. Since 1961 UK CVD deaths and [age standardised] death rates have fallen by more than half.
Treatment for CAD involves lifestyle changes, if necessary, drugs and certain medical procedures. Various drugs that are used to treat CAD are Cholesterol-modifying medications, Beta blockers, Nitroglycerin, Angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs). Some of the Procedures to restore and improve blood flow like Angioplasty and stent placement (percutaneous coronary revascularization), Coronary artery bypass surgery.
Some of the major researches on Coronary artery disease in UK are impaired vascular function and repair in patients with premature coronary artery disease, Management of concomitant coronary artery disease in patients undergoing transcatheter aortic valve implantation: The United Kingdom TAVI Registry.