Hemangioma originally described any vascular tumor-like structure, whether it was present at or around birth or appeared later in life. Mulliken et al. categorized these conditions into two families: one of self-involuting tumors, growing lesions that eventually disappear, and another of malformations, enlarged or abnormal vessels present at birth and essentially permanent. The importance of this distinction is that it makes it possible for early-in-life differentiation between lesions that will resolve versus those that are permanent.
Signs and symptoms : If they are on the surface of the skin, they are reminiscent of a ripe strawberry (hence, they are sometimes referred to as "strawberry hemangiomas"). If they are just under the skin they present as a bluish swelling. Sometimes they grow in internal organs such as the liver, larynx, or small and large intestines.In most cases, hemangiomas will disappear over time. Some are formed during gestation and are called congenital hemangiomas; the most common (infantile hemangiomas) appear during the first few weeks of life.
Causes : The cause of hemangioma is currently unknown; however, several studies have suggested the importance of estrogen signaling in hemangioma proliferation. In 2007, a paper from the Stanford Children's Surgical Laboratory revealed that localized soft tissue hypoxia coupled with increased circulating estrogen after birth may be the stimulus.
Statistics: According to the case report and literature review by Vokaer et al, since 1898 when Van Haefen described the first case of spontaneous rupture of a liver hemangioma, only 33 cases of ruptured hemangioma in adults have been reported in the literature. Spontaneous rupture of this tumor is an uncommon complication, representing 1%-4% in Jain’s case series (spontaneous rupture with hemoperitoneum) and 2.9% in the study of Chen et al (a study of 70 cases admitted from 1992-2001 with spontaneous liver rupture including primary liver cancer, cirrhosis, liver adenoma.