Haemophilus influenzae type B vaccine is a conjugate vaccine for the prevention of infectious disease caused by Haemophilus influenzae type b bacteria. The Haemophilus influenzae (Hib) vaccine have reduced childhood meningitis. A Hib bacterium is a Gram-negative, coccobacillar, facultative anaerobic pathogenic bacterium.
Hib causes bacteremia, pneumonia, epiglottitis and acute bacterial meningitis. It causes cellulitis, osteomyelitis, and infectious arthritis. It causes epiglottitis, Pneumonia- Fever, Cough, Chills, Sweating, Chest pain, Bacteremia- Diarrhea, and Vomiting and Meningitis. Treatment of Hib infection includes Cortisone and antibiotics like Cefotaxime, Clarithromycin and fluoroquinolones.
Out of 2,111 cases of invasive H. influenzae infections reported in children in England and Wales between 1994 and 2008, including 1,831 isolates with known serotype, only 3 cases of Hib were found. Children who survive Hib meningitis are left with some type of serious permanent damage, such as mental retardation, deafness, epilepsy, or partial blindness.