alexa Lichen planus | United-kingdom | PDF | PPT| Case Reports | Symptoms | Treatment

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Lichen Planus

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  • Lichen planus

    Lichen planus is an inflammatory condition which affects the skin and mucous membranes. It is a T-cell–mediated autoimmune disease in which autocytotoxic CD8+ T cells trigger apoptosis of oral epithelial cells. On the skin, lichen planus usually appears as purplish, often itchy, flat-topped bumps. In mouth, vagina and other areas covered by a mucous membrane, lichen planus forms lacy white patches, sometimes with painful sores. There is no cure for Lichen planus. Treatment for the skin may include Antihistamines, Corticosteroides, Retinoic acid.

  • Lichen planus

    The largest UK patient group with oral lichen planus (OLP) was studied in terms of the demographic and clinical characteristics. Reticular OLP was the most common intra-oral presentation, but 60% of such lesions were accompanied by other clinical types of OLP. 95% of lesions were bilateral. About 13% of patients reported symptoms or signs, or had a known history of lichen planus or possible lichen planus affecting non-oral epithelia. In only 13% of patients did all signs and symptoms of OLP resolve within 12-246 months (median 35 months). A malignant transformation rate of 1.9% was observed in the present group.

 

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