Osteosarcoma is a bone tumor and can occur in any bone, usually in the extremities of long bones near metaphyseal growth plates. The most common sites are long bones A number of variants of osteosarcoma exist, including conventional types (osteoblastic, chondroblastic, and fibroblastic), telangiectatic, multifocal, parosteal, and periosteal. In about 75% of cases, patients with osteosarcoma are between 15–25 years of age. Male are more frequently affected than female (ration 1.5:1). Osteosarcoma rarely occurs in patients younger than 6 years or older than 60 years.
Tumours observed in older age usually develop secondary to Paget's disease, radiation or dedifferentiated chondrosarcomas. Osteosarcoma is treated by using these class of drugs such as Antineoplastic agents, Antiemetic agents, Antidotes. Immunotherapy drugs: Clinical trials are looking into ways to help the patient’s own immune system recognize and attack the osteosarcoma cells. A new drug called muramyl tripeptide (MTP) has been shown to help some patients when added to chemotherapy.