History of sclerosing mesenteritis is not well understood, because of the rarity of this condition. In a five-year follow-up report of 47 patients with mesenteric Sclerosing mesenteritis, 65 percent were alive, and in those who died, one-half of the deaths were due to malignancy (50 percent carcinoma, 50 percent lymphoma) In another series, 12 percent of patients developed malignancy, including lymphoma, carcinoid syndrome, lung adenocarcinoma, and mesothelioma. Fulminant cases of sclerosing mesenteritis have been reported and are largely due to complications of intestinal obstruction.
sclerosing mesenteritis is asymptomatic, gastrointestinal symptoms such as abdominal pain, nausea/vomiting, bloating, loss of appetite, weight loss and diarrhea or constipation, Occasionally, intermittent partial bowel obstruction is encountered. Non-gastrointestinal symptoms include fatigue, weight loss, night sweats and fever.
Sclerosing mesenteritis occurs when the tissue mesentery that holds the small intestines in place becomes inflamed and forms scar tissue.Sclerosing mesenteritis can cause abdominal pain, bloating and diarrhea. In rare cases, scar tissue formed by sclerosing mesenteritis can block food from moving through your digestive tract. Surgery may be necessary in this situation.