alexa Progeria | United States| PDF | PPT| Case Reports | Symptoms | Treatment

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  • Progeria

    For parents who have already had a child with Progeria, the chances of it happening again to those parents is much higher – about 2-3%. Why the increase? This is due to a condition called “mosaicism”, where a parent has the genetic mutation for Progeria in a small proportion of their cells, but does not have Progeria. Prenatal testing is available to look for the LMNA genetic change that causes HGPS.
  • Progeria

    Therapeutic aspects

    No treatment has demonstrated successful. Most treatment focuses on lessening intricacies, (for example, cardiovascular infection) with corocoronary artery bypass surgery or low-doseaspirin. Children might likewise profit by a high-vitality diet. Development hormone treatment has been endeavored. The utilization of Morpholinos has additionally been endeavored so as to lessen progerin generation. Farnesyltransferase inhibitors (FTIs) are medications that restrain the movement of a chemical required with a specific end goal to make a connection between progerin proteins and farnesyl bunches. Pravastatin, exchanged as Pravachol or Selektine, is incorporated into the group of statins. And additionally zoledronate (otherwise called Zometa and Reclast, which is a bisphosphonate), its utility in HGPS is the counteractive action of farnesyl gathering arrangement, which progerin needs to provoke the disease.


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