Vector

Gene Technology is one of the top leading journals in biomedical engineering which publishes novel research articles after rigorous peer-review process by at least 2 expert reviewers of the associated fields. Modern Biotechnology are interesting fields in which expression of genes, taking advantage of natural genetic variation, modifying genes and transferring genes to new hosts, Environmental Biotechnology, Cell biology, Genetic Engineering and Molecular Biology, Tissue Engineering, Biosensor, Cancer Biology, Bioinformatics and Computational biology are covered. Gene targeting via homologous recombination (HR) provides the definitive tool in analyzing gene function. For gene targeting to be successfully achieved, the target genome sequence should be replaced with the vector DNA (i.e., targeting vector), not with the sister chromatid. The principal limitation of conventional gene-targeting technology is the extremely low efficiency of HR-mediated targeted integration, which occurs at least 2-3 orders of magnitude less frequently than random integration. “Noritaka Adachi, Repair of Accidental DNA Double-Strand Breaks in the Human Genome and Its Relevance to Vector DNA Integration” OMICS is devoted to the prompt publication of original findings of the highest scientific priority and value that provide novel mechanistic insights, represent a clear advance over previous Studies and have the potential to generate exciting future research.

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Last date updated on April, 2024