Parameters
Test (mean±S.D.)
Reference (mean±S.D.)
Cmax (ng ml-1)
1052.47±254.41
1039.10±301.54
AUC(0-t) (ng h ml-1)
8737.48±1545.24
8850.04±1892.63
AUC(0-∞) (ng h ml-1)
9622.12±1692.57
9695.02±2133.95
tmax (h)
3.04±0.93
3.07±1.39
Kel (h-1)
0.10±0.06
0.10±0.03
t½ (h)
7.44±1.85
7.24±2.10
Table 1: Mean pharmacokinetic parameters of the test and the reference formulations, each containing 100 mg troxipide.