Subject
No. |
Cmax (ng ml-1) |
tmax (h) |
AUC(0-∞) (ng h ml-1) |
t½(h) |
T |
R |
T |
R |
T |
R |
T |
R |
1 |
799.08 |
911.11 |
3.00 |
3.00 |
8753.57 |
9487.34 |
7.09 |
6.84 |
2 |
883.78 |
887.04 |
4.00 |
4.00 |
9568.62 |
8720.77 |
6.04 |
6.88 |
3 |
1028.91 |
1109.32 |
2.00 |
2.25 |
7690.52 |
7802.36 |
6.38 |
5.34 |
4 |
976.03 |
1156.16 |
4.00 |
1.75 |
7503.11 |
7367.40 |
8.47 |
3.98 |
5 |
1138.33 |
941.83 |
3.00 |
1.50 |
10829.48 |
10285.06 |
8.56 |
9.04 |
6 |
775.67 |
784.36 |
2.50 |
4.00 |
9589.38 |
8495.11 |
7.80 |
6.31 |
7 |
1417.71 |
1334.77 |
1.50 |
2.50 |
10526.81 |
12753.17 |
8.34 |
11.72 |
8 |
604.82 |
994.83 |
4.00 |
4.00 |
8401.16 |
8420.81 |
9.42 |
6.64 |
10 |
947.14 |
689.95 |
2.50 |
4.00 |
11439.25 |
8097.64 |
10.13 |
6.12 |
11 |
1112.86 |
1384.44 |
2.50 |
3.00 |
11274.99 |
11984.79 |
6.53 |
8.70 |
12 |
1510.66 |
1148.57 |
3.00 |
2.50 |
11019.72 |
9784.15 |
9.27 |
6.57 |
13 |
1212.22 |
1010.86 |
3.00 |
2.50 |
12631.57 |
13055.71 |
7.96 |
10.88 |
14 |
1151.42 |
1688.02 |
3.00 |
2.25 |
9006.08 |
12416.02 |
6.06 |
9.06 |
15 |
1439.83 |
1088.63 |
3.00 |
1.50 |
11862.95 |
11136.76 |
8.87 |
6.86 |
16 |
1000.87 |
948.27 |
3.00 |
1.00 |
10286.17 |
10574.18 |
7.43 |
4.72 |
17 |
918.23 |
927.78 |
2.50 |
3.00 |
9939.87 |
9623.49 |
7.02 |
6.25 |
18 |
1566.97 |
1387.58 |
2.50 |
2.50 |
11054.97 |
10815.13 |
7.94 |
6.44 |
19 |
927.12 |
875.15 |
2.25 |
4.00 |
8210.91 |
7535.56 |
5.73 |
5.87 |
20 |
1128.64 |
1164.70 |
4.00 |
4.00 |
8862.32 |
10680.57 |
5.57 |
6.66 |
21 |
1068.02 |
1743.02 |
2.25 |
0.50 |
12008.48 |
14132.78 |
10.91 |
11.92 |
22 |
621.66 |
554.61 |
6.00 |
4.00 |
7838.56 |
6236.41 |
5.75 |
6.87 |
23 |
816.35 |
717.49 |
2.50 |
4.00 |
6764.54 |
7559.23 |
7.96 |
7.41 |
24 |
1167.44 |
761.01 |
3.00 |
6.00 |
9115.66 |
9034.30 |
7.32 |
8.26 |
26 |
1045.55 |
728.97 |
4.00 |
6.00 |
6752.09 |
6681.80 |
1.88 |
4.39 |
|
