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| Figure 4: 90% confidence intervals for artesunate, dihydroartemisinin and dose-normalised mefloquine pharmacokinetic parameters obtained after single oral doses of artesunate and mefloquine given as a Fixed formulation (200 mg artesunate/400 mg mefloquine) or a Non-Fixed formulation (200 mg artesunate + 500 mg mefloquine) to healthy volunteers. Data expressed as 90% confidence intervals around the ratio (% Fixed/Non-Fixed) of geometric least square means. |
