Parameter

Test

Reference

t1/2 (h)

4.39±2.52

4.86±4.50

Tmax (h)

3.35±1.12

3.69±1.08

AUC0–12 (μg/mL·h)

12.77±3.22

13.99±3.95

AUC0~∞ (μg/mL·h)

16.02±5.65

17.20±6.67

Cmax (μg/mL)

1.96±0.40

2.07±0.62

Table 4: Main pharmacokinetic parameters of uridine after single oral dose of 600 mg citicoline sodium test and reference (image±s, n=24).
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