Parameter |
Liq.Tc:Oleic |
10%DPY patch |
Control
patch |
Cmax (ng/ml) |
514.8 ± 150.83 |
219.0 ± 36.5 |
20.2 ± 2.0 |
tmax (min.) |
114.0 ± 13.41 |
408.0 ± 107.3 |
204.0 ± 32.8 |
Kel (min-1) |
0.0012 ± 0.0005 |
0.0030 ± 0.0004 |
0.0010 ± 0.0005 |
t1/2 (min.) |
571.1 ± 24.8 |
264.2 ± 36.1 |
620.6 ± 293.5 |
AUCinf (ng*min/ml) |
485972 ±148347 |
124636 ± 19811 |
20715 ± 9357 |
MRT (min.) |
880.3 ± 18.2 |
527.9 ± 30.9 |
929.1 ± 442.4 |
All formulae between the same brackets are not significantly different from each
other but differ significantly from those included in other brackets (P<0.001)
Cmax (ng/ml): (Liq.Tc:Oleic) (10%DPY patch) (Control Patch)
AUC(0–∞) (ng*min/ml): (Liq.Tc:Oleic) (10%DPY patch) (Control Patch) |
