| Pharmacokinetic Parameters |
Test (T) |
Reference (R) |
T/R |
I C 90% for Mean Ratio** |
| Mean* |
SD |
Mean* |
SD |
| Tmax (h) |
1.82 |
0.81 |
1.54 |
0.75 |
- |
- |
| Cmax (ng/mL) |
879.30 |
345.00 |
884.30 |
501.10 |
106.84% |
93.63% - 121.92% |
| Kel |
0.24 |
0.14 |
0.24 |
0.12 |
- |
- |
| T1/2 (h) |
4.70 |
5.36 |
3.86 |
2.70 |
- |
- |
| AUC0-t (ng.h/mL) |
2137.70 |
795.40 |
2107.30 |
1058.50 |
105.83% |
96.80% - 115.72% |
| AUC0-∞ (ng.h/mL) |
2233.80 |
768.70 |
2183.00 |
1061.00 |
107.52% |
98.45% - 117.43% |
* Arithmetic mean; ** Geometric mean; IC = Confidence intervals; SD = Standard deviation |
