Viagra Conventional Film-Coated Tablet (n=30) Chewable Tablet With Water (n=30) Chewable Tablet Without Water (n=30) Tmax, h Mean (SD) Median CV, % 1.42 (0.95) 1.00 66.7 1.03 (0.68) 0.75 66.7 1.62 (0.80) 1.75 49.2 Cmax, ng/mL Mean (SD) Median CV, % 657.64 (332.58) 640.85 50.6 556.75 (196.79) 506. 92 35.4 517.46 (244.20) 448.80 47.2 AUC0-t, h•ng/mL Mean (SD) Median CV,% 1884.97(923.22) 1668. 87 49.0 1803.45 (859.73) 1571.24 47.7 1680.04 (790.69) 1423.47 47.1 AUC0-inf, h•ng/mL Mean (SD) Median CV,% 1983.03 (1006.63) 1744.81 50.8 1907.12 (978.50) 1630.51 51.3 1797.13 (881.35) 1502.24 49.0 Ke, per h Mean (SD) Median CV,% 0.259 (0.094) 0.252 36.5 0.269 (0.079) 0.282 29.2 0.244 (0.094) 0.252 38.3 t1/2, h Mean (SD) Median CV, % 3.06 (1.23) 2.76 40.1 2.94 (1.43) 2.46 48.7 3.45 (1.88) 2.76 54.6 AUC0-inf=area under the plasma concentration vs time curve from time 0 extrapolated to infinity; AUC0-t=area under the plasma concentration vs time curve from time 0 to time t; Cmax=maximum plasma concentration; CV=coefficient of variation; Ke=elimination rate constant; t½=elimination half life; Tmax=time to reach Cmax.

Table 1: Pharmacokinetic Variables for Sildenafil 100 mg.

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