| Topic |
Procedure |
Note |
Raw data |
Log-data |
Comment |
| crossover |
Carry over effect |
Point |
-9.59167 |
-0.073641 |
No difference in carry over effect |
| p-value |
0.546808 |
0.395214 |
| C.I. |
(-42.1,22.9) |
(-0.25,0.10) |
| |
Direct drug effect |
Point |
-2.2875 |
-0.0124434 |
No difference in direct drug effect |
| p-value |
0.546334 |
0.612057 |
| C.I. |
(-10.03,5.45) |
(-.63,.038) |
| |
Period effect |
Point |
-1.73125 |
-0.0119826 |
No difference in period effect |
| p-value |
0.647392 |
0.625221 |
| C.I. |
(-9.47,6.01) |
(-.062,.038) |
| |
Equality of variances |
p-value |
0.942656 |
0.951822 |
Equal variances |
| Indexes |
PSR index |
|
0.834627 |
0.957676 |
Bio-equivalent |
| |
Shannon index |
Kernel |
1.02169 |
1.12405 |
Bio-equivalent |
| C.I. |
Band Interval |
Simulation |
(91.67,100) |
(95.8,95.8) |
Bio-equivalent |
| |
Classical |
|
(89.56,104.99) |
(97.16,101.53) |
Bio-equivalent |
| |
Based on Fieller’s theorem |
|
(90.88,104.10) |
(97.22,101.52) |
Bio-equivalent |
| |
Schuirmann |
|
(89.85,105.20) |
(97.19,105.46) |
Bio-equivalent |
| Tests |
Schuirmann two one-sided |
|
|
Bio-equivalent |
| |
Anderson |
p-value |
0.00029844 |
0.00000000 |
Bio-equivalent |
| |
Equality of means |
p-value |
0.701094 |
0.712434 |
Bio-equivalent |
| |
Power |
Power |
0.98404 |
1.000000 |
Bio-equivalent |
|
