Parameter |
Test |
Vfend™ （reference） |
Cmax (ng/mL) |
925.73 ± 356.11 |
1040.25 ± 448.93 |
Tmax (h) |
1.57 ± 0.98 |
1.38±0.96 |
AUC0-t (ng/mL*h) |
5304.97 ±3072.25 |
5141.63±2976.92 |
AUC0-∞ (ng/mL*h) |
5783.21 ± 3266.86 |
5520.69 ± 3148.42 |
T1/2 (h) |
7.80±2.16 |
6.77±2.05 |
Cmax, maximum plasma concentration; Tmax, time to peak concentration; AUC0-t,
area under plasma concentration-time curve from zero to the last measurable
concentration; AUC0-∞, area under plasma concentration time curve from zero to
infinity; T1/2, elimination half-life |
